The fasting plasma glucose is correlated to the prevalence and severity of coronary artery disease in population without diabetes history in Xinjiang, China

摘要

The aim of the study is to investigate the association of fasting plasma glucose (FPG) with the prevalence and severity of coronary artery disease (CAD) in different ethnic groups without diabetes history in Xinjiang. Patients without diabetes history, who had undergone coronary angiography, were obtained. The levels of FPG in different ethnics were analyzed. The Gensini score was explored to evaluate the degree of coronary artery stenosis, and the logistic regression analysis was adopted to explore the risk factors of the prevalence of CAD. A total of 1500 cases (men 71.2; mean age 57.6 ± 10.6 years; 1095 cases of CAD) were included. The incidence rates of CAD were 76.8 in Han, 72.5 in Uyghur and 68.1 in Kazakh group, respectively (P = .009), while the Gensini scores in Kazahk group (36.63 ± 33.88) were lower than the other ethnic populations (P = .003). The FPG levels in patients with CAD were significant higher than that without in all the ethnic groups (P  = 1.22, 95CI 1.07–1.39, P = .003), as well as the age, sex, smoking or hypertension history, were associated with the CAD risk. FPG level was an independent risk factor of the prevalence and severity of CAD in population in Xinjiang.