Restless legs syndrome and cerebrovascular disease.Authors' reply

摘要

We thank GianPietro Sechi and Elia Sechi for their comments in response to our Review about movement disorders in cerebrovascular disease. One of the authors previously reported the case of a 48.year.old woman who developed bilateral restless legs syndrome (RLS) within 3 days of a right lenticulo. striate lacunar stroke. Although the temporal association was striking, no explanation was provided for how a unilateral basal ganglia lesion induced a bilateral movement disorder not typically associated with observable striatal pathology. A year later, Lee and colleagues reported that 17 (12%) of 137 patients without a history of RLS developed RLS phenomenology within 1 month of an acute stroke. RLS was reported most widely in patients with strokes in the basal ganglia or corona radiata, pons, lateral thalamus, and the internal capsule.