We read with interest Maarten Titulaer and colleagues'1 comprehensive analysis of presenting features and outcomes in 577 patients with anti-NMDA receptor (NMDAR) encephalitis. Patients with autoimmune encephalitis can present to either neurology or psychiatry services, dependent on the presence of behavioural or neurological symptoms. Increasingly, neurologists are asked to exclude autoimmune causes for acute psychosis in patients attending psychiatric services. Many of these patients do not have typical features of anti-NMDAR encephalitis; however, because some evidence exists for the presence of anti-NMDAR (and other antineuronal) antibodies in patients with schizophrenia without other features of encephalitis,2 testing for anti-NMDAR antibodies might be done in these patients.
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