Nuclear medicine and large animal studies in the pharmacological development of psychotropics

摘要

Nowadays, brain diseases account for a third of the entire disease burden in the world . The role of psychiatric disorders, with unipolar depressive disorders as a striking example, is taking a prominent place in the global disease burden and health costs. The updated WHO Global Burden of Disease publication on the leading causes of disability adjusted life years (DALYs) listed unipolar depressive disorders (UDP) on rank 4 in 2002. WHO reliably forecasts that unipolar depressive disorders will be ranked in second place in 2030, only preceded by the HIV/AIDS-related burden. It is noteworthy that unipolar depressive disorders in the WHO projections for 2030 will be ranked number 1 in the high-income countries but also, respectively, numbers 2 and 3 in the middle-income and low-income countries. The conclusion is to classify this disorder as a global burden of disease that needs urgent attention