Local ablative non-surgical procedures for non-small-cell lung cancer

摘要

abstract_textpUntil recently conventional radiotherapy was the gold standard in the treatment of stage I non-small-cell lung cancer if a surgical approach was not possible due to severe comorbidities. This review summarizes the current status of modern local ablative approaches. The technique of stereotactic body radiotherapy (SBRT) consistently achieves local control rates of 90 and improves overall survival compared to conventional radiotherapy. SBRT is a safe procedure and provides a curative option for elderly patients and patients with very poor pulmonary function. Local tumor control after radiofrequency ablation is at best 70 and below 50 for tumors 3 cm. Consequently, SBRT is considered as non-surgical the treatment of choice./p/abstract_text