Intact point-light walker processing in Williams syndrome: a magnetoencephalography study

摘要

Williams syndrome (WS) is a rare genetic disorder that results in profound spatial cognitive deficits. Several behavioral studies have showed that point-light walker (PLW) perception is intact in children and adults with WS; however, the neural responses underlying PLW perception ir adults with WS have not been fully investigated. In this study we studied an adult with WS by magnetoencephalography. We introduced a novel experimental technique to extract a neuromagnetic response relating to PLW perception, and then evaluated how this response differed from that in normal adults. The peak amplitude and latency of neuromagnetic responses were within 2 SD of the means among normal adults