Real-life experience with fampridine (Fampyra (R)) for patients with multiple sclerosis and gait disorders

Fragoso Yara Dadalti; Adoni Tarso; Alves-Leon Soniza Vieira; Apostolos-Pereira Samira Luisa; Barreira Amilton Antunes; Bidin Brooks Joseph Bruno; Claudino Rinaldo; Correa Eber Castro; Brito Ferreira Maria Lucia; Finkelsztejn Alessandro; Finkelsztejn Juliana; da Gama Paulo Diniz; Magno Goncalves Marcus Vinicius; Guerreiro Carlos Tostes; da Cunha Matta Andre Palma; Marques Vanessa Daccach; Morales Rogerio Rizo; Koncke Parolin Monica Fiuza; Ribeiro Marlise de Castro; Gonsalves Jube Ribeiro Taysa Alexandrino; Ruocco Heloisa Helena; Sato Henry; Scherpenhuijzen Simone; Siquineli Fabio; de Carvalho Sousa Nise Alessandra; Varela Daniel Lima; Tauil Carlos Bernardo; Winckler Thereza Cristina

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Real-life experience with fampridine (Fampyra (R)) for patients with multiple sclerosis and gait disorders

机译：患有多发性硬化症和步态障碍的患者使用甲氨蝶呤（Fampyra（R））的真实经验

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BACKGROUND: Fampridine is a broad-spectrum voltage-dependent potassium channel blocker that enhances synaptic transmission. The drug has been shown to be able to ameliorate conduction in demyelinated axons, thereby leading to improved gait in patients with multiple sclerosis (MS).

机译：背景：氨苯吡啶是一种广谱的电压依赖性钾通道阻滞剂，可增强突触传递。已显示该药物能够改善脱髓鞘轴突的传导，从而改善多发性硬化症（MS）患者的步态。

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来源
《NeuroRehabilitation》 |2016年第2期|共4页
作者
Fragoso Yara Dadalti; Adoni Tarso; Alves-Leon Soniza Vieira; Apostolos-Pereira Samira Luisa; Barreira Amilton Antunes; Bidin Brooks Joseph Bruno; Claudino Rinaldo; Correa Eber Castro; Brito Ferreira Maria Lucia; Finkelsztejn Alessandro; Finkelsztejn Juliana; da Gama Paulo Diniz; Magno Goncalves Marcus Vinicius; Guerreiro Carlos Tostes; da Cunha Matta Andre Palma; Marques Vanessa Daccach; Morales Rogerio Rizo; Koncke Parolin Monica Fiuza; Ribeiro Marlise de Castro; Gonsalves Jube Ribeiro Taysa Alexandrino; Ruocco Heloisa Helena; Sato Henry; Scherpenhuijzen Simone; Siquineli Fabio; de Carvalho Sousa Nise Alessandra; Varela Daniel Lima; Tauil Carlos Bernardo; Winckler Thereza Cristina;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Multiple sclerosis; gait; walking; fampridine;

机译：多发性硬化;步态;行走;氨苯吡啶;

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专利

1. Real-life experience with fampridine (Fampyra (R)) for patients with multiple sclerosis and gait disorders [J] . Fragoso Yara Dadalti, Adoni Tarso, Alves-Leon Soniza Vieira, NeuroRehabilitation . 2016,第2期

机译：患有多发性硬化症和步态障碍的患者使用甲氨蝶呤（Fampyra（R））的真实经验
2. Predicting responsiveness to fampridine (Fampyra (R)) in gait-impaired people with multiple sclerosis [J] . Filli Linard, Werner Jana, Reuter Katja, Multiple sclerosis: clinical and laboratory research . 2018,第6期

机译：预测对患有多发性硬化症的步态受损人群的Fampridine（Fampyra（R））的反应性
3. Predicting responsiveness to fampridine in gait-impaired patients with multiple sclerosis [J] . Filli L., Werner J., Beyer G., European journal of neurology: the official journal of the European Federation of Neurological Societies . 2019,第2期

机译：预测多发性硬化症患者的Gait障碍患者对Fampridine的反应性
4. Measuring changes in gait kinematics due to walking-related fatigue in patients with Multiple Sclerosis [C] . Juri Taborri, Valeria Studer, Paola Grossi, IEEE International Symposium on Medical Measurements and Applications . 2019

机译：测量多发性硬化症患者行走相关疲劳导致的步态运动学变化
5. The effects of fatigue and disease severity on gait mechanics in subjects with multiple sclerosis. [D] . Marchesi, Stephanie J. 2007

机译：疲劳和疾病严重程度对多发性硬化患者步态力学的影响。
6. Cortical Excitability Measures May Predict Clinical Response to Fampridine in Patients with Multiple Sclerosis and Gait Impairment [O] . Rechdi Ahdab, Madiha M. Shatila, Abed Rahman Shatila, 2019

机译：皮质兴奋性措施可能预测多发性硬化和步态障碍患者对甲氨蝶呤的临床反应
7. The Role of Fampridine in the Symptomatic Treatment of Gait Impairment in Patients with Multiple Sclerosis [O] . Michał Piwoński, Klaudia Żak, Patrycja Gierszon, 2019

机译：群普利汀在多发性硬化症患者的症状治疗症状中的作用

Real-life experience with fampridine (Fampyra (R)) for patients with multiple sclerosis and gait disorders

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