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Calcifying odontogenic cyst

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The calcifying odontogenic cyst designated by Gorlin et al. in 1962 is a cystic lesion of the odontogenic origin which is characterized histologically by keratinizing ghost cell and its calcification. Recently, neoplastic potential of this lesion has been pointed out by several investigators and this lesion has been considered to be a borderline lesion between cyst and tumor. From the view point of neoplastic potential of this lesion, we evaluated 8 cases of calcifying odontogenic cyst encountered in our hospital within 12 years from 1972 to 1984. Our cases were divided into two types, cystic and proliferative. Clinical differential diagnoses of the cystic type were globulomaxillary cyst, primordial cyst and cystic odontoma, while those of the proliferative type were ameloblastoma and calcifying epithelial odontogenic tumor. There wre 2 cases of the proliferative type among all the cases. One of them was recurrent lesion with 20 years' duration. We agreed to the designation of “calcifying ghost cell odontogenic tumor”, proposed by Fejerscov and Krogh, rather than calcifying odontogenic cyst. Furthermore, we propose to sub-classify it into cystic type and proliferative t

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