Feeding Regimens and Necrotising Enterocolitis Concerning the Article by C. Maas et al.: A Historic Cohort Study on Accelerated Advancement of Enteral Feeding Volumes in Very Premature Infants [Neonatology 2013; 67-73]

摘要

We read with interest the paper by Maas et al. [1] comparing a 'conservative' (starting with 10-15 ml/kg/day on day 1 and then advancing by 15-20 ml/kg/day) with an 'accelerated' (20 ml/kg/day on day 1 and advanced by 25-30 ml/kg/day) enteral feeding regimen. The main outcome parameter was to assess the effects of accelerated enteral feeding on time until on full feeds (> =140 ml/kg/day), on early postnatal growth as well as on the rate of necrotizing enterocolitis (NEC). In their study, the time to establish full enteral feeds was shorter in the accelerated feeding group (6; 5-9 days) compared to the conservative group (8; 7-11 days).