Osteoarthritis: Crystal-gazing into the pathogenesis of osteoarthritis

摘要

The precise role that basic calcium phosphate microcrystals have in the pathogenesis of osteoarthritis (OA) is controversial. The recent paper by Jin et al. provides new insights into the potential mechanisms that link these microcrystals to joint damage, and highlights the role of the NLRP3 inflammasome in the pathogenesis of OA.