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首页> 外文期刊>Nature reviews. Urology >Stearoyl-CoA desaturase: A novel therapeutic target for RCC
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Stearoyl-CoA desaturase: A novel therapeutic target for RCC

机译:硬脂酰辅酶A去饱和酶:RCC的新型治疗靶标

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摘要

Outcomes for patients with advanced clear cell renal cell carcinoma (ccRCC) are discouraging. The currently available therapeutic options for these patients have not been shown to improve long-term survival, and although medications have recently been approved for use in patients with advanced disease, so far none have proven curative and combination protocols are problematic owing to toxicity caused by the non-tumour-specific effects of the drugs.
机译:晚期透明细胞肾细胞癌(ccRCC)患者的结局令人沮丧。对于这些患者的当前可用治疗选择尚未显示出改善长期生存的趋势,尽管最近已批准将药物用于晚期疾病患者,但迄今为止,由于由丙二醛引起的毒性,尚无经证实的治疗方法和联合方案存在问题药物的非肿瘤特异性作用。

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