Triterpene Saponins from the Sea Cucumber Stichopus chloronotus

摘要

Sea cucumbers have been used as a dietary delicacy and important ingredient in Asian traditional medicine and functional foods over many centuries. Using combined chromatographic methods, six triterpene saponins (1-6), including a new compound, stichloroside F (1), were isolated from a methanol extract of the sea cucumber Stichopus chloronotus Brandt. Their structures were determined on the basis of spectroscopic (~1H and ~(13)C NMR, HSQC, HMBC, ~1H-~1H COSY, ROESY) and FTICR-MS data and by comparison with literature values.