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New hopane triterpenes and antioxidant constituents from Potentilla fulgens

机译:委陵菜新的hop烷三萜和抗氧化剂成分

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Phytochemical investigation of the aerial parts of Potentilla fulgens L. led to the isolation of two new triterpenes, potentene A (1) and potentene B (2). In addition, three known compounds afzelchin-4→8″-catechin (3), epiafzelchin (4) and rutin (5) were isolated. The structures of all these compounds were elucidated by extensive spectroscopic and chemical evidence. Compounds 3, 4, and 5 exhibited significant 1,1,diphenyl-2-picrylhydrazyl radical scavenging activity, with IC_(50) values of 1.21, 2.88 and 5.20 mg/mL, respectively; the known standard antioxidant, vitamin C, had a value of 0.44 mg/mL.
机译:对白叶委陵菜(Potentilla fulgens L.)空中部分的植物化学研究导致分离出两个新的三萜,即戊烯A(1)和戊烯B(2)。另外,分离了三种已知的化合物afzelchin-4→8″-儿茶素(3),表阿afzelchin(4)和芦丁(5)。广泛的光谱和化学证据阐明了所有这些化合物的结构。化合物3、4和5表现出明显的1,1,1,1-二苯基-2-吡啶并肼基自由基清除活性,IC_(50)值分别为1.21、2.88和5.20 mg / mL。已知的标准抗氧化剂维生素C的值为0.44 mg / mL。

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