NMDA receptors on oligodendrocytes

摘要

The prevailing view that white matter otigodendrocytes lack NMDA(N-methyl-D-aspartate)-type glutamate receptors seems to have been wrong, according to three papers published recently in Nature. The reports provide compelling evidence for the involvement of oligodendrocyte NMDA receptors in glutamate-mediated damage to these cells in injury and disease.