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Purpose. - The aim of this work was to establish the acquisition, calculation and 3D compensator manufacturing optimum parameters. This methodology is based on virtual simulation and 3D dosimetry. Materials and Methods. - The material used is a helicoidal CT (PQ 5000-Marconi), a virtual simulation system (AcQsim version 4-Marconi), a Treatment Planning System (Dosigray), a linear accelerator Saturne 43 (Varian, CGR), an automated milling system for compensator filters (Autimo 2.5 D-HEK), a water tank phantom (wellhofer) and an homogeneous phantom with simple patterns in order to simulate the obliquity surface of patient body. The compensator was composed by granulate tin because this material ensures a good profile modulation. The compensation plane has been calculated at 80% to dose profile. The compensator thickness profile has been calculated with different acquisition (slice thickness, pitch factor), calculation (attenuation coefficient, bixel) and fabrication parameters (drill diameter, specification of milling system). Results. - After this preliminary study, we have defined the optimum parameters for the compensator realization. We have observed that the slice thickness, bixel size and drill diameter are the parameters that mainly affect the profiles homogeneity. The choice of parameters with smaller dimensions S = 3 mm; B = 3 mm, F = 3 mm, improve the profiles homogeneity. Though, for manufacture times compatible with the clinical routine, the selected parameters are S = 5 mm, B = 6 mm and F = 6 mm. Compensator can be used for any type of Linac. However, one must pay attention on their realization and their positioning on the beam central axis.
机译:目的。 -这项工作的目的是建立采集,计算和3D补偿器制造的最佳参数。该方法基于虚拟仿真和3D剂量学。材料和方法。 -使用的材料是螺旋CT(PQ 5000-Marconi),虚拟模拟系统(AcQsim 4-Marconi版本),治疗计划系统(Dosigray),线性加速器Saturne 43(Varian,CGR),自动铣削系统用于补偿器过滤器(Autimo 2.5 D-HEK),水箱体模(wellhofer)和具有简单图案的均质体模,以模拟患者身体的倾斜表面。补偿器由锡粒组成,因为这种材料可确保良好的轮廓调制。补偿平面已计算为剂量分布的80%。通过不同的采集(切片厚度,螺距系数),计算(衰减系数,bixel)和制造参数(钻头直径,铣削系统规格)来计算补偿器厚度曲线。结果。 -经过初步研究,我们为补偿器的实现定义了最佳参数。我们已经观察到,切片厚度,bixel尺寸和钻头直径是主要影响轮廓均匀性的参数。较小尺寸的参数选择S = 3 mm; B = 3 mm,F = 3 mm,可改善轮廓的均匀性。但是,为了使制造时间与临床程序兼容,所选参数为S = 5 mm,B = 6 mm和F = 6 mm。补偿器可用于任何类型的直线加速器。但是,必须注意它们的实现及其在光束中心轴上的定位。

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