SYNTHESIS OF 4,5-DIAMINOPYRROLO1,2-aQUINOLINE DERIVATIVES BY A LEWIS ACID CATALYZED REACTION OF 2-(PYRROL-1-YL)BENZALDIMINES WITH ISOCYANIDES

摘要

N-Alkyl(or aryl)-2-(pyrrol-1-yl)benzaldimines,derived from 2-(pyrrol-1-yl)benzaldehydes and primary amines,were treated with aromatic and aliphatic isocyanides in the presence of a catalytic amount of boron trifluoride diethyl etherate to afford the corresponding 4,5-diaminopyrrolo1,2-aquinoline derivatives in generally fair to good yields.