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Antibacterial Activity Composition of the Fermentation Broth of Streptomyces djakartensis NW35

机译:djakartensis NW35链霉菌发酵液的抗菌活性成分

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摘要

The new compound Z-4-2 was isolated from the fermentation broth of Streptomyces djakartensis NW35, together with the known compound N-acetyltryptamine (Z-9-2) by bioassay-guided fractionation. Its chemical structure was elucidated as (E)-2- methoxy-1,4 naphthoquinone-1-oxime (Z-4-2) mainly by NMR analyses and MS spectral data. Their antibacterial activities against bacteria were evaluated by the filter paper method. The results of indicated that these compounds possess significant antibacterial activities.
机译:通过生物测定引导分级分离法,从djakartensis链霉菌NW35的发酵液中分离出新化合物Z-4-2,并与已知化合物N-乙酰色胺(Z-9-2)分离。主要通过NMR分析和MS光谱数据阐明其化学结构为(E)-2-甲氧基-1,4-萘醌-1-肟(Z-4-2)。通过滤纸法评估它们对细菌的抗菌活性。结果表明这些化合物具有显着的抗菌活性。

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