Mechanism of cancer-induced fatigue

摘要

Cancer related fatigue (CRF) is one of the mostcommon and painful reactions in cancer patients. Due to thenegative effects of cancer itself and long-term treatment,patients often feel continuous burnout, fatigue andpowerlessness in both mental and physical aspects. Fatiguerelated to cancer and cancer treatment will affect the physicaland mental health of cancer patients for a long time andcontinuously, and it is hard to be relieved through rest.Nowadays, most of the researches focus on the clinicalmanifestations of patients with cancer, such as pain, nauseaand vomiting, weight loss and so on. The fatigue feeling ofcancer patients is often one of the most easily overlooked painsymptoms in the treatment process. The influence of CRF oncancer patients may be one of the reasons for reducing thesurvival time of cancer patients. This paper aims tosummarize and explore the pathogenesis of cancer-relatedfatigue, in order to analyze the related factors of cancerrelated fatigue from multi-dimensional and multi-angle, andprovide reference for its comprehensive treatment in clinic.