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Recent applications of multicomponent reactions in medicinal chemistry

机译:多组分反应在药物化学中的最新应用

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摘要

Multicomponent reactions are flexible reactions for the rapid generation of complex molecules with often biologically relevant scaffold structures. Combined with the ease of parallelization and the exploratory power with regard to chemical space, multicomponent reactions have attracted significant attention from the medicinal chemistry community. In this Review, we present an overview of recent literature concerning this topic to provide insight into the applications of multicomponent reactions in this field.
机译:多组分反应是柔性反应,用于快速生成通常具有生物学相关支架结构的复杂分子。结合平行化的难易程度和对化学空间的探索能力,多组分反应引起了药物化学界的极大关注。在本综述中,我们提供了有关该主题的最新文献的概述,以深入了解多组分反应在该领域的应用。

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