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Comparison of Doxorubicin Anticancer Drug Loading on Different Metal Oxide Nanoparticles

机译:不同金属氧化物纳米颗粒上阿霉素抗癌药载量的比较

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摘要

Nanomaterials are being vigorously investigated for their use in anticancer drug delivery regimes or as biomarkers agents and are considered to be a candidate to provide a way to combat severe weaknesses of anticancer drug pharmacokinetics, such as their nonspecificity. Because of this weakness, a bigger proportion of the drug-loaded nanomaterials flow toward healthy tissues and result in undesirable side effects. It is very important to evaluate drug loading and release efficiency of various nanomaterials to find out true pharmacokinetics of these drugs.
机译:纳米材料正被广泛研究其在抗癌药物递送方案中的用途或作为生物标记剂的用途,被认为是提供解决抗癌药物药代动力学严重缺陷(例如其非特异性)的方法的候选材料。由于这种弱点,较大比例的载有药物的纳米材料流向健康组织,并导致不良副作用。评估各种纳米材料的载药量和释放效率以找出这些药物的真实药代动力学非常重要。

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