Positron Emission Tomography With F-18-Fluorodeoxyglucose in Patients With Sickle Cell Acute Chest Syndrome

摘要

The acute chest syndrome (ACS) is the main cause of mortality among adult patients with sickle cell disease (SCD). Its pathophysiology is still unclear. Using positron emission tomography (PET) with F-18-fluorodeoxyglucose [F-18-fluorodeoxyglucose (F-18-FDG)], we explored the relationship between regional lung density and lung metabolism, as a reflection of lung neutrophilic infiltration during ACS.