High Delta-Like Ligand 4 (DLL4) Is Correlated With Peritumoral Brain Edema and Predicts Poor Prognosis in Primary Glioblastoma

摘要

Delta-like ligand 4 (DLL4), 1 of the 5 known Notch ligands, is involved in a variety of tumor initiation and progression, particularly in the process of tumor angiogenesis. However, the clinical and prognostic significance of DLL4 in glioblastoma have not been fully elucidated.