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Skin dose in longitudinal and transverse linac-MRIs using Monte Carlo and realistic 3D MRI field models

机译:使用Monte Carlo和逼真的3D MRI场模型在纵向和横向直线加速器MRI中的皮肤剂量

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Purpose: The magnetic fields of linac-MR systems modify the path of contaminant electrons in photon beams, which alters patient skin dose. To accurately quantify the magnitude of changes in skin dose, the authors use Monte Carlo calculations that incorporate realistic 3D magnetic field models of longitudinal and transverse linac-MR systems. Methods: Finite element method (FEM) is used to generate complete 3D magnetic field maps for 0.56 T longitudinal and transverse linac-MR magnet assemblies, as well as for representative 0.5 and 1.0 T Helmholtz MRI systems. EGSnrc simulations implementing these 3D magnetic fields are performed. The geometry for the BEAMnrc simulations incorporates the Varian 600C 6 MV linac, magnet poles, the yoke, and the magnetic shields of the linac-MRIs. Resulting phase-space files are used to calculate the central axis percent depth-doses in a water phantom and 2D skin dose distributions for 70 μm entrance and exit layers using DOSXYZnrc. For comparison, skin doses are also calculated in the absence of magnetic field, and using a 1D magnetic field with an unrealistically large fringe field. The effects of photon field size, air gap (longitudinal configuration), and angle of obliquity (transverse configuration) are also investigated. Results: Realistic modeling of the 3D magnetic fields shows that fringe fields decay rapidly and have a very small magnitude at the linac head. As a result, longitudinal linac-MR systems mostly confine contaminant electrons that are generated in the air gap and have an insignificant effect on electrons produced further upstream. The increase in the skin dose for the longitudinal configuration compared to the zero B-field case varies from ~1 to ~14 for air gaps of 5-31 cm, respectively. (All dose changes are reported as a of D max.) The increase is also field-size dependent, ranging from ~3 at 20 × 20 cm 2 to ~11 at 5 × 5 cm 2. The small changes in skin dose are in contrast to significant increases that are calculated for the unrealistic 1D magnetic field. For the transverse configuration, the entrance skin dose is equal or smaller than that of the zero B-field case for perpendicular beams. For a 10 × 10 cm 2 oblique beam the transverse magnetic field decreases the entry skin dose for oblique angles less than ±20° and increases it by no more than 10 for larger angles up to ±45°. The exit skin dose is increased by 42 for a 10 × 10 cm 2 perpendicular beam, but appreciably drops and approaches the zero B-field case for large oblique angles of incidence. Conclusions: For longitudinal linac-MR systems only a small increase in the entrance skin dose is predicted, due to the rapid decay of the realistic magnetic fringe fields. For transverse linac-MR systems, changes to the entrance skin dose are small for most scenarios. For the same geometry, on the exit side a fairly large increase is observed for perpendicular beams, but significantly drops for large oblique angles of incidence. The observed effects on skin dose are not expected to limit the application of linac-MR systems in either the longitudinal or transverse configuration.
机译:目的:直线加速器-MR系统的磁场会改变光子束中污染物电子的路径,从而改变患者的皮肤剂量。为了准确量化皮肤剂量变化的幅度,作者使用了蒙特卡洛计算方法,该方法结合了纵向和横向直线加速器-MR系统的逼真的3D磁场模型。方法:有限元方法(FEM)用于为0.56 T纵向和横向直线加速器-MR磁体组件以及代表性的0.5和1.0 T亥姆霍兹MRI系统生成完整的3D磁场图。执行实现这些3D磁场的EGSnrc仿真。 BEAMnrc仿真的几何结构结合了Varian 600C 6 MV直线加速器,磁极,磁轭和直线加速器MRI的磁屏蔽。生成的相空间文件用于使用DOSXYZnrc计算70微米入口和出口层的水模中的中心轴深度剂量百分比和2D皮肤剂量分布。为了进行比较,还可以在不存在磁场的情况下,并使用具有不切实际的大边缘场的一维磁场来计算皮肤剂量。还研究了光子场大小,气隙(纵向构型)和倾斜角(横向构型)的影响。结果:对3D磁场的真实建模显示,边缘场迅速衰减,并且在直线加速器头部的幅度很小。结果,纵向直线加速器-MR系统主要限制了在气隙中产生的污染电子,并且这些污染物对上游产生的电子影响不大。与零B场情况相比,纵向配置的皮肤剂量增加对于气隙为5-31 cm的范围从〜1到〜14不等。 (所有剂量变化均以D max的形式报告。)这种增加还取决于场大小,范围从20×20 cm 2的〜3到5×5 cm 2的〜11。与不现实的一维磁场计算得出的显着增加形成对比。对于横向配置,入射皮肤的剂量等于或小于垂直光束的零B场情况。对于10×10 cm 2的倾斜光束,对于小于±20°的倾斜角,横向磁场会减小进入皮肤的剂量,而对于最大角度为±45°的倾斜角,横向磁场的入射皮肤剂量不会超过10。对于10×10 cm 2的垂直光束,出射皮肤剂量增加42,但是对于大的斜入射角,出射皮肤剂量明显下降并接近零B场。结论:对于纵向直线加速器-MR系统,由于现实的电磁条纹场的快速衰减,仅预测了入口皮肤剂量的少量增加。对于横向直线加速器-MR系统,在大多数情况下,进入皮肤剂量的变化很小。对于相同的几何形状,在出射侧对于垂直光束观察到相当大的增加,但是对于大的倾斜入射角则明显下降。预期观察到的对皮肤剂量的影响不会限制直线加速器-MR系统在纵向或横向配置中的应用。

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