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Determining the incident electron fluence for Monte Carlo-based photon treatment planning using a standard measured data set.

机译:使用标准测量数据集确定基于蒙特卡洛的光子治疗计划的入射电子注量。

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An accurate dose calculation in phantom and patient geometries requires an accurate description of the radiation source. Errors in the radiation source description are propagated through the dose calculation. With the emergence of linear accelerators whose dosimetric characteristics are similar to within measurement uncertainty, the same radiation source description can be used as the input to dose calculation for treatment planning at many institutions with the same linear accelerator model. Our goal in the current research was to determine the initial electron fluence above the linear accelerator target for such an accelerator to allow a dose calculation in water to within 1% or 1 mm of the measured data supplied by the manufacturer. The method used for both the radiation source description and the patient transport was Monte Carlo. The linac geometry was input into the Monte Carlo code using the accelerator's manufacturer's specifications. Assumptions about the initial electron source above the target were made based on previous studies. The free parameters derived for the calculations were the mean energy and radial Gaussian width of the initial electron fluence and the target density. A combination of the free parameters yielded an initial electron fluence that, when transported through the linear accelerator and into the phantom, allowed a dose-calculation agreement to the experimental ion chamber data to within the specified criteria at both 6 and 18 MV nominal beam energies, except near the surface, particularly for the 18 MV beam. To save time during Monte Carlo treatment planning, the initial electron fluence was transported through part of the treatment head to a plane between the monitor chambers and the jaws and saved as phase-space files. These files are used for clinical Monte Carlo-based treatment planning and are freely available from the authors.
机译:在幻影和患者的几何形状中进行准确的剂量计算需要对放射源进行准确的描述。辐射源描述中的错误会通过剂量计算传播。随着线性加速器的出现,其剂量特性类似于测量不确定度之内,在许多具有相同线性加速器模型的机构中,相同的辐射源描述可以用作剂量计算的输入,以用于治疗计划。我们当前研究的目标是确定这种加速器的线性加速器目标上方的初始电子注量,以使水中的剂量计算在制造商提供的测量数据的1%或1 mm之内。用于辐射源描述和患者运输的方法是蒙特卡洛。使用加速器制造商的规格将直线加速器的几何形状输入到蒙特卡洛代码中。根据先前的研究对目标上方的初始电子源进行了假设。计算得出的自由参数是初始电子注量的平均能量和径向高斯宽度以及目标密度。自由参数的组合产生了初始电子注量,当通过线性加速器传输到幻像中时,在6和18 MV标称束能量下,实验离子室数据的剂量计算协议均在指定的标准之内,除了表面附近,特别是对于18 MV光束。为了节省蒙特卡洛治疗计划期间的时间,最初的电子注量通过治疗头的一部分传输到监护室和钳口之间的平面,并保存为相空间文件。这些文件用于基于蒙特卡洛的临床治疗计划,可从作者那里免费获得。

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