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A method for geometrical verification of dynamic intensity modulated radiotherapy using a scanning electronic portal imaging device.

机译:一种使用扫描电子门禁成像设备对动态强度调制放射疗法进行几何验证的方法。

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In order to guarantee the safe delivery of dynamic intensity modulated radiotherapy (IMRT), verification of the leaf trajectories during the treatment is necessary. Our aim in this study is to develop a method for on-line verification of leaf trajectories using an electronic portal imaging device with scanning read-out, independent of the multileaf collimator. Examples of such scanning imagers are electronic portal imaging devices (EPIDs) based on liquid-filled ionization chambers and those based on amorphous silicon. Portal images were acquired continuously with a liquid-filled ionization chamber EPID during the delivery, together with the signal of treatment progress that is generated by the accelerator. For each portal image, the prescribed leaf and diaphragm positions were computed from the dynamic prescription and the progress information. Motion distortion effects of the leaves are corrected based on the treatment progress that is recorded for each image row. The aperture formed by the prescribed leaves and diaphragms is used as the reference field edge, while the actual field edge is found using a maximum-gradient edge detector. The errors in leaf and diaphragm position are found from the deviations between the reference field edge and the detected field edge. Earlier measurements of the dynamic EPID response show that the accuracy of the detected field edge is better than 1 mm. To ensure that the verification is independent of inaccuracies in the acquired progress signal, the signal was checked with diode measurements beforehand. The method was tested on three different dynamic prescriptions. Using the described method, we correctly reproduced the distorted field edges. Verifying a single portal image took 0.1 s on an 866 MHz personal computer. Two flaws in the control system of our experimental dynamic multileaf collimator were correctly revealed with our method. First, the errors in leaf position increase with leaf speed, indicating a delay of approximately 0.8 s in the control system. Second, the accuracy of the leaves and diaphragms depends on the direction of motion. In conclusion, the described verification method is suitable for detailed verification of leaf trajectories during dynamic IMRT.
机译:为了保证安全地进行动态强度调制放射治疗(IMRT),必须在治疗过程中验证叶片轨迹。我们在这项研究中的目的是开发一种方法,该方法使用具有扫描读数的电子门禁成像设备独立于多叶准直仪来在线验证叶片轨迹。这种扫描成像器的示例是基于液体填充电离室的电子门成像设备(EPID)和基于非晶硅的电子门成像设备。在输送过程中,用充满液体的电离室EPID连续获取门静脉图像,并结合加速器产生的治疗进展信号。对于每个门户图像,根据动态处方和进度信息计算指定的叶子和隔膜位置。根据记录在每个图像行上的处理进度来校正叶片的运动失真效果。由规定的叶片和膜片形成的孔径用作参考场边缘,而实际的场边缘使用最大梯度边缘检测器找到。叶片和膜片位置的误差可从参考场边缘和检测到的场边缘之间的偏差中找到。动态EPID响应的早期测量表明,检测到的场边缘的精度优于1 mm。为了确保验证与所采集的进度信号中的不准确性无关,请事先通过二极管测量来检查该信号。该方法在三种不同的动态处方上进行了测试。使用所描述的方法,我们正确地再现了失真的场边缘。验证单个门户网站映像在866 MHz个人计算机上花费了0.1 s。我们的方法正确地揭示了我们的实验动态多叶准直仪控制系统中的两个缺陷。首先,叶片位置的误差随着叶片速度的增加而增加,这表明控制系统中的延迟约为0.8 s。其次,叶片和隔膜的精度取决于运动方向。总之,所描述的验证方法适用于动态IMRT期间叶轨迹的详细验证。

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