Validation of simplified dosimetry approaches in 89Zr-PET/CT: The use of manual versus semi-automatic delineation methods to estimate organ absorbed doses

摘要

Purpose: Increasing interest in immuno-positron emission tomography (PET) studies requires development of dosimetry methods which will provide accurate estimations of organ absorbed doses. The purpose of this study is to develop and validate simplified dosimetry approaches for 89Zirconium-PET (Zr-PET)/computed tomography (CT) studies.