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首页> 外文期刊>Medical Physics >A new water-equivalent 2D plastic scintillation detectors array for the dosimetry of megavoltage energy photon beams in radiation therapy.
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A new water-equivalent 2D plastic scintillation detectors array for the dosimetry of megavoltage energy photon beams in radiation therapy.

机译:一种新型的等效于水的二维塑料闪烁探测器阵列,用于放射治疗中兆伏能量光子束的剂量测定。

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摘要

PURPOSE: The objective of this work is to present a new 2D plastic scintillation detectors array (2D-PSDA) designed for the dosimetry of megavoltage (MV) energy photon beams in radiation therapy and to characterize its basic performance. METHODS: We developed a 2D detector array consisting of 781 plastic scintillation detectors (PSDs) inserted into a plane of a water-equivalent phantom. The PSDs were distributed on a 26 x 26 cm(2) grid, with an interdetector spacing of 10 mm, except for two perpendicular lines centered on the detection plane, where the spacing was 5 mm. Each PSD was made of a 1 mm diameter by 3 mm long cylindrical polystyrene scintillating fiber coupled to a clear nonscintillating plastic optical fiber. All of the light signals emitted by the PSDs were read simultaneously with an optical system at a rate of one measurement per second. We characterized the performance of the optical system, the angular dependency of the device, and the perturbation of dose distributions caused by the hundreds of PSDs inserted into the phantom. We also evaluated the capacity of the system to monitor complex multileaf collimator (MLC) sequences such as those encountered in step-and-shoot intensity modulated radiation therapy (IMRT) plans. We compared our results with calculations performed by a treatment planning system and with measurements taken with a 2D ionization chamber array and with a radiochromic film. RESULTS: The detector array that we developed allowed us to measure doses with an average precision of better than 1% for cumulated doses equal to or greater than 6.3 cGy. Our results showed that the dose distributions produced by the 6-MV photon beam are not perturbed (within +/-1.1%) by the presence of the hundreds of PSDs located into the phantom. The results also showed that the variations in the beam incidences have little effect on the dose response of the device. For all incidences tested, the passing rates of the gamma tests between the 2D-PSDA and the treatment planning system were higher than 97.5% when the standard clinical tolerances of 3% or 3 mm were used. Excellent agreement was obtained between the doses measured and calculated when we used the 2D-PSDA for monitoring a MLC sequence from a step-and-shoot IMRT plan. CONCLUSIONS: We demonstrated the feasibility of using a large number of PSDs in a new 2D-PSDA for the dosimetry of MV energy photon beams in radiation therapy. The excellent precision, accuracy, and low angular dependence of the device indicate that such a prototype could potentially be used as a high-accuracy quality assurance tool for IMRT and arc therapy patient plan verification. The homogeneity and water-equivalence of the prototype we built suggest that this technology could be extended to multiple detection planes by arranging the fibers into more complex orientations, opening the possibility for 3D dosimetry with PSDs.
机译:目的:这项工作的目的是提出一种新的二维塑料闪烁探测器阵列(2D-PSDA),其设计用于放射治疗中的兆伏(MV)能量光子束的剂量测定,并表征其基本性能。方法:我们开发了一个二维检测器阵列,该阵列由781个塑料闪烁检测器(PSD)组成,该检测器插入了等效于水的模型中。 PSD分布在26 x 26 cm(2)的网格上,检测器之间的间距为10 mm,但两条垂直线位于检测平面上,其中间距为5 mm。每个PSD由直径为1毫米,长度为3毫米的圆柱形聚苯乙烯闪烁纤维制成,并耦合到透明的非闪烁塑料光纤上。 PSD发出的所有光信号均以每秒一次测量的速率与光学系统同时读取。我们表征了光学系统的性能,设备的角度依赖性以及由插入幻像仪中的数百个PSD引起的剂量分布扰动。我们还评估了系统监视复杂的多叶准直仪(MLC)序列(例如,步调强度调制放射治疗(IMRT)计划中遇到的序列)的能力。我们将结果与治疗计划系统进行的计算,二维电离室阵列和放射致变色膜的测量结果进行了比较。结果:我们开发的检测器阵列使我们能够对等于或大于6.3 cGy的累积剂量进行平均精度优于1%的剂量测量。我们的研究结果表明,位于模型中的数百个PSD不会干扰6-MV光子束产生的剂量分布(在+/- 1.1%范围内)。结果还表明,光束入射角的变化对设备的剂量响应影响很小。对于所有测试的发病率,当使用3%或3 mm的标准临床公差时,在2D-PSDA和治疗计划系统之间的伽玛测试通过率均高于97.5%。当我们使用2D-PSDA监测IMRT计划中的MLC序列时,在测量和计算的剂量之间获得了极好的一致性。结论:我们证明了在新型2D-PSDA中使用大量PSD进行放射治疗中MV能量光子束剂量测定的可行性。该设备出色的精度,准确性和低角度依赖性表明,这种原型可以潜在地用作IMRT和电弧疗法患者计划验证的高精度质量保证工具。我们构建的原型的均质性和水等效性表明,通过将纤维排列成更复杂的方向,可以将该技术扩展到多个检测平面,从而为使用PSD进行3D剂量测定打开了可能性。

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