Letters to the Editor-Beyond Beauty: Botulinum Toxin Use in Anal Fissure

摘要

I read with interest the article on use of Botox in Anal fissure, Beyond Beauty: Botulinum Toxin Use in Anal fissure MJAFI 2009;65:213-5. I have following observations regarding the methodology employed and the conclusions drawn. The patients in the ibid study continued to be on standard conservative regime for chronic anal fissure (High roughage diet and topical 2% Lignocaine jelly) even after they received Botox injection. Therefore, the pain relief reported by the author cannot be solely attributed to injection Botox. This conclusion would have been valid if there had been a control group in the study which had solely received the conservative regime.