Accutane registry compulsory in US, but not Canada. medicale canadienne

摘要

The United States has ramped up efforts to mitigate the risk of birth defects associated with isotretinoin (Accutane) by requiring physicians and patients to register before they can prescribe or take the drug. The response in Canada has been markedly less stringent, despite recommendations lastyear from a federal government expert advisory committee. Isotretinoin, used to treat recalcitrant nodular acne, is known to have serious side effects, including birth defects, severe depression and, potentially, vascular incidents.