The detection of nonpolypoid (flat and depressed) colorectal neoplasms in patients with inflammatory bowel disease

摘要

Random biopsy is recommended in the US to detect flat dysplasia in patients with colonic inflammatory bowel disease (cIBD), despite its known poor sensitivity and the significant risk of missing flat dysplasia. Herein, we describe pancolonic chromoendos-copy (CE) using indigo carmine (Akorn, Inc, Lake Forest, IL) with targeted biopsy which is proven to be more sensitive for detecting flat dysplasia in cIBD.