Combination Therapy of Ursodeoxycholic Acid and Corticosteroids for Primary Biliary Cirrhosis with Features of Autoimmune Hepatitiss A Meta- Analysis

摘要

Primary biliary cirrhosis (PBC) and autoimmune hepatitis (AIH) are two autoimmune diseases that have major effects on the liver. Each disease has its own clinical manifestations and immunological and histological features [1]. However, some patients may display the characteristics of both diseases. For example, patients with PBC with features of AIH have the characteristics of both PBC and AIH simultaneously [2]. According to the study by Czaja [3], the incidence of PBC-AIH in autoimmune liver disease is 7%. Chazouilleres et al. [4] concluded that the incidence of PBC-AIH in PBC is 9.2%.