Initial experience with a risk-sharing in vitro fertilization-embryo transfer program with novel features.

摘要

OBJECTIVE: To describe outcomes of the first 100 consecutive infertility patients participating in a risk-sharing program with uncomplicated eligibility requirements. The program included the costs of FSH-containing gonadotropin preparations and provided a full payment refund if no birth occurred that resulted in a normal infant surviving to an age of 1 month. DESIGN: Retrospective cohort study. SETTING: Private IVF center. PATIENT(S): Infertility patients<35 years of age, considered to be good autologous oocyte IVF candidates at time of program enrollment. INTERVENTION(S): Retrospective analysis of outcomes of fresh IVF-ET and frozen embryo transfer cycles involving conventional treatment protocols. MAIN OUTCOME MEASURE(S): Cumulative successful pregnancy rate. RESULT(S): Of the first 100 patients enrolled in the program, 82 have had a delivery of a normal infant surviving to an age of 1 month, and another 6 have undelivered ongoing pregnancies at 20+ weeks. Nine participants completed the program without completing a successful treatment cycle, and another three remain enrolled. CONCLUSION(S): Infertility patients<35 years of age participating in a risk-sharing program with uncomplicated eligibility requirements are very likely to have a successful pregnancy. Other centers may wish to incorporate some of the described program's features into their own risk-sharing IVF programs.