Ammonium carbamate;mild,selective and efficient ammonia source for preparation of beta-amino-alpha,beta-unsaturated esters at room temperature

摘要

Ammonium carbamate can be used as a very effective reagent for preparation of different substituted beta-amino-alpha,beta-unsaturated esters in methanol at room temperature,The product is isolated without aqueous work-up in high purity and excellent yield,The method is simple and easily scaled-up.