Pd-catalyzed Dehalogenation of Aromatic Halides Under Solvent-free Conditions Using Hydrogen Balloon

摘要

The dehalogenation of aromatic halides possesses great significance not only in the removal of halogenated organic contaminants but also in the development of synthetic methodologies. Although several processes have already been well established to deal with toxic and even carcinogenic aryl halides, including adsorption and inactivation by oxidation and incineration methods, there is still a need for alternative treatments because conventional treatments unavoidably result in the production of highly deleterious by-products or huge amounts of waste materials. Solvent-free (solvent-less) reactions have attracted much attention because they have several advantages over traditional reactions in organic liquid solvents: smaller reaction vessels, no organic medium to make less wastes, higher efficiency, easier operation, simpler purification and different product distribution. Chemical reductive dehalogenation, by means of the hydrogenolysis of the carbon-halogen bond to remove halogen atoms in molecules, has attracted attention from the field of both industry and academics.