CIK cells--current status, clinical perspectives and future prospects--the good news.

摘要

There is an ongoing explosion of knowledge in pursuing the adoptive immunother-apy of cancer to offer an alternative and/or supplementary approach for the treatment of human cancer refractory to conventional therapies. Important issues for developing effective adoptive immunotherapy strategies include the generation of sufficient functional immune effectors, the efficient recognition and lysis of tumor targets by the effectors and overcoming the restriction to specific human leukocyte antigen (HLA) haplotypes.