Synthesis of Quinoline N-Oxides from the Baylis-Hillman Adducts of 2-Nitrobenzaldehydes:Conjugate Addition of Nitroso Intermediate

摘要

The Baylis-Hillman reaction is a useful carbon-carbon bond-forming method from activated vinyls and carbonyl compounds.Chemical transformation of the Baylis-Hillman adducts or their derivatives into useful heterocyclic compounds has been studied recently by us and other groups.Especially,conversion of the Baylis-Hillman adducts derived from 2-nitrobenzaldehydes into quinoline skeleton is a useful entry for the quinoline chemistry.