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Review: colorectal cancer screening with the faecal occult blood test reduced colorectal cancer mortality.

机译:回顾:用粪便潜血试验筛查大肠癌可降低大肠癌死亡率。

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Colorectal cancer is a global problem that accounts for about 655000 deaths each year worldwide.1 Precancerous polyps can remain in situ for years before cancer develops, and early detection with polyp removal effectively decreases colorectal cancer incidence. Early treatment of cotorectal cancer increases survival. Despite these benefits, screening rates remain low.2 The Cochrahe systematic review by Hewifson ef al updates a previous review and provides strong evidence that annual faecal occult blood screening with diagnostic evaluation reduces cancer mortality when compared with no screening. Strengths of the review are a rigorous methodology and discussion of the risks and benefits of screening. On a cautionary note, a high rate of false positives was found in most of the included studies. This would lead to negative psychosocial or physical sequalae for a substantial number of people who complete the screening test. Another limitation of the review is the inability to detect any decrease in all-cause mortality because of difficulty tn measuring the effect of comorbidities on patients with colorectal cancer.Population screening is recommended to decrease colorectal cancer incidence and mortality. Specific groups at increased risk of colorectal cancer are ageing people and those with a family history of the disease. Implications of this review are particularly relevant to nursing because nurses typically provide patient education. The authors recommend further research on the information needs of individuals before screening and on the type of information that should be provided. Recently, Wackerbarth ef a discussed 10 areas that influence decision making. Nurses should address these areas with people who are considering colorectal cancer screening.
机译:结直肠癌是一个全球性问题,全世界每年约有655,000例死亡。1癌前息肉可以在癌症发展之前就位多年,并且通过息肉清除的早期发现可以有效降低结直肠癌的发病率。直肠直肠癌的早期治疗可提高生存率。尽管有这些好处,筛查率仍然很低。2Hewifson等人的Cochrahe系统评价更新了以前的评价,并提供有力证据表明,与不进行筛查相比,每年的粪便潜血筛查和诊断评估可以降低癌症死亡率。审查的优势是采用严格的方法并讨论筛查的风险和收益。请注意,在大多数纳入研究中发现了较高的假阳性率。对于完成筛查测试的相当多的人来说,这将导致负面的社会心理或生理状况。综述的另一个局限性是由于难以测量合并症对大肠癌患者的影响而无法检测到全因死亡率的降低。建议进行人群筛查以降低大肠癌的发病率和死亡率。罹患结直肠癌风险增加的特定人群是老龄化人群和有该病家族史的人群。由于护士通常会提供患者教育,因此本次审查的含义与护理特别相关。作者建议对个人在筛选之前的信息需求以及应提供的信息类型进行进一步研究。最近,Wackerbarth等人讨论了影响决策的10个领域。护士应与正在考虑进行大肠癌筛查的人员联系起来。

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