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Spontaneous haemorrhage in an eyelid hidrocystoma in a patient treated with clopidogrel

机译:氯吡格雷治疗的患者的眼睑水囊瘤自发性出血

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A 62-year-old woman presented with a lesion on the medial aspect of the left upper lid, which was slowly enlarging over 2 years and darkened 6 months earlier. She admitted to having excessive sun exposure in the past, and her past medical history included hypertension, type II diabetes, and peripheral vascular disease. Her regular medications were insulin, metformin, simvastatin, ramipril, and clopidogrel.Examination revealed a curious lesion on the medial aspect of the left upper lid (Figure la). The lesion, which appeared cystic and lobulated, was mostly skin coloured with surface telangiectasia and purple-blue discoloration inferiorly. Although a benign lesion was suspected, the unusual appearance prompted excisional biopsy. Histopathological examination showed a papillary hidrocystoma with apocrine differentiation, featuring small lakes of blood within the myxoid material occupying the lumen (Figure lb).
机译:一名62岁的女性左上眼睑内侧出现病变,在2年内逐渐增大,在6个月前变黑。她承认过去曾暴露于过度的阳光下,她的既往病史包括高血压,II型糖尿病和周围血管疾病。她的常规药物是胰岛素,二甲双胍,辛伐他汀,雷米普利和氯吡格雷。检查发现左上眼睑内侧有奇怪的病变(图1a)。病灶呈囊性和小叶状,大部分为皮肤着色,表面毛细血管扩张和紫蓝色变色。尽管怀疑有良性病变,但异常外观提示行切除活检。组织病理学检查显示乳头状水囊瘤具有顶分泌分化,其特征是在粘液样物质内的小湖区占据了内腔(图1b)。

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