The therapeutic management of gut barrier leaking: the emerging role for mucosal barrier protectors

Lopetuso L. R.; Scaldaferri F.; Bruno G.; Petito V.; Franceschi F.; Gasbarrini A.

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The therapeutic management of gut barrier leaking: the emerging role for mucosal barrier protectors

机译：肠道屏障泄漏的治疗管理：黏膜屏障保护剂的新兴作用

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OBJECTIVE: Gut barrier is a functional unit organized as a multi-layer system and its multiple functions are crucial for maintaining gut homeostasis. Numerous scientific evidences showed a significant association between gut barrier leaking and gastro-intestinal/extra-intestinal diseases.

机译：目的：肠道屏障是一个组织为多层系统的功能单元，其多种功能对于维持肠道稳态至关重要。大量科学证据表明，肠屏障泄漏与胃肠道/肠外疾病之间存在显着关联。

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《European review for medical and pharmacological sciences.》 |2015年第6期|共9页
作者
Lopetuso L. R.; Scaldaferri F.; Bruno G.; Petito V.; Franceschi F.; Gasbarrini A.;
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正文语种 eng
中图分类药理学;
关键词
Gut barrier; Mucus; Gut microbiota; Gelatin tannate; Mucosal protectors; Gut barrier enhancer;

机译：肠屏障;粘液;肠道菌群;明胶明胶;粘膜保护剂;肠屏障增强剂;

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专利

1. The therapeutic management of gut barrier leaking: the emerging role for mucosal barrier protectors [J] . Lopetuso L. R., Scaldaferri F., Bruno G., European review for medical and pharmacological sciences. . 2015,第6期

机译：肠道屏障泄漏的治疗管理：黏膜屏障保护剂的新兴作用
2. The gut's role in metabolism, mucosal barrier function, and gut immunology. [J] . DeWitt RC, Kudsk KA Infectious disease clinics of North America . 1999,第2期

机译：肠道在新陈代谢，粘膜屏障功能和肠道免疫学中的作用。
3. Gut Mucosal Barrier Dysfunction, Microbial Dysbiosis, and Their Role in HIV-1 Disease Progression [J] . Mudd Joseph C., Brenchley Jason M. The Journal of Infectious Diseases . 2016,第S2期

机译：肠粘膜屏障功能障碍，微生物代谢障碍及其在HIV-1疾病进展中的作用
4. Mediators of Blood-Brain Barrier Disruption and Potential Therapeutic Interventions for Protection of the Barrier Following Focal Ischemia [C] . Stephen N. Ponnampalam, Marc R. Mayberg Congress of Neurological Surgeons . 2004

机译：血脑屏障中断和潜在治疗干预措施，用于保护局灶性缺血后屏蔽的潜在治疗干预措施
5. Breaking the Mucosal Barrier: Investigating the Role of MicroRNA in the Disruption of the Intestinal Epithelial Barrier During SIV Infection [D] . Gaulke, Christopher Andrew. 2014

机译：打破粘膜屏障：SIV感染过程中调查MicroRNA在肠上皮屏障破坏中的作用
6. Gelatin tannate ameliorates acute colitis in mice by reinforcing mucus layer and modulating gut microbiota composition: Emerging role for ‘gut barrier protectors’ in IBD? [O] . Franco Scaldaferri, Loris Riccardo Lopetuso, Valentina Petito, 2014

机译：明胶单宁酸盐通过增强粘液层和调节肠道菌群组成改善小鼠急性结肠炎：IBD中肠屏障保护剂的新兴作用？
7. Gelatin tannate ameliorates acute colitis in mice by reinforcing mucus layer and modulating gut microbiota composition: Emerging role for 'gut barrier protectors' in IBD? [O] . Scaldaferri, Franco, Lopetuso, Loris Riccardo, Petito, Valentina, 2014

机译：明胶单宁酸盐通过增强粘液层和调节肠道菌群组成改善小鼠急性结肠炎：IBD中“肠屏障保护剂”的新兴作用？

The therapeutic management of gut barrier leaking: the emerging role for mucosal barrier protectors

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