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首页> 外文期刊>European journal of epidemiology >Active and passive smoking and the risk of myocardial infarction in 24,968 men and women during 11 year of follow-up: The Troms? Study
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Active and passive smoking and the risk of myocardial infarction in 24,968 men and women during 11 year of follow-up: The Troms? Study

机译:在随访的11年中,有24,968名男性和女性主动和被动吸烟以及发生心肌梗塞的风险:Troms?研究

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摘要

Active smoking is a well-established risk factor for myocardial infarction, but less is known about the impact of passive smoking, and possible sex differences in risk related to passive smoking. We investigated active and passive smoking as risk factors for myocardial infarction in an 11-year follow-up of 11,762 men and 13,206 women included in the Troms? Study. There were a total of 769 and 453 incident cases of myocardial infarction in men and women, respectively. We found linear age-adjusted relationships between both active and passive smoking and myocardial infarction incidence in both sexes. The relationships seem to be stronger for women than for men. Age-adjusted analyses indicated a stronger relationship with passive smoking in ever-smokers than in never-smokers. After adjustment for important confounders (body mass index, blood pressure, total cholesterol, HDL cholesterol and physical activity) the associations with active and passive smoking were still statistically significant. Adjusting for active smoking when assessing the effect of passive smoking and vice versa, indicated that the effect of passive smoking in men may be explained by their own active smoking. In women, living with a smoker ≥30 years after the age of 20 increased the myocardial infarction risk by 40 %, even after adjusting for active smoking. Passive smoking is a risk factor for myocardial infarction on its own, but whereas the effect for men seems to be explained by their own active smoking, the effect in females remains statistically significant.
机译:主动吸烟是公认的心肌梗死危险因素,但对于被动吸烟的影响以及与被动吸烟相关的风险中可能存在的性别差异知之甚少。我们对Troms纳入的11762名男性和13206名女性进行了11年的随访,调查了主动和被动吸烟是心肌梗死的危险因素。研究。男性和女性分别有769和453例心肌梗塞事件。我们发现男女之间主动和被动吸烟与心肌梗塞发生率之间的年龄校正线性关系。女人的关系似乎比男人更牢固。年龄调整后的分析表明,与从未吸烟者相比,经常吸烟者与被动吸烟的关系更强。在对重要的混杂因素(体重指数,血压,总胆固醇,高密度脂蛋白胆固醇和体育锻炼)进行调整后,主动和被动吸烟的相关性仍具有统计学意义。在评估被动吸烟的效果时调整主动吸烟,反之亦然,这表明被动吸烟对男性的影响可能由他们自己的主动吸烟来解释。在女性中,即使在调整了主动吸烟后,在20岁之后吸烟者≥30岁的女性,其心肌梗塞风险也会增加40%。被动吸烟本身就是造成心肌梗塞的危险因素,但是,尽管对男性的影响似乎可以通过主动吸烟来解释,但对女性的影响仍具有统计学意义。

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