[(1,3-Bis{2,6-bis(diphenylmethyl)-4-methylphenyl}imidazole- 2-ylidene)PdCl_2(NEt3)]: 'Throwing Away' a Different Ancillary Ligand to Enhance the Catalytic Activity at Room Temperature

摘要

A considerable effort in ligand design for catalysis in recent years has led to remarkable achievements in cross-coupling reactions. In this work, we show that a careful selection of the ancillary ligands that complete the catalyst/precatalyst can provide an extra level of performance. Low loadings of [(IPr*)PdCl_2(TEA)] {IPr* = 1,3-bis[2,6-bis(diphenylmethyl)-4-methylphenyl]imidazole-2-ylidene, TEA = triethylamine} catalyze the Buchwald-Hartwig amination reactions of aryl chlorides at room temperature in excellent yields, without the need for an inert atmosphere to set up or perform the reactions.