Penile syringoma in a 14-year-old boy.

摘要

Syringomas, benign tumors of the eccrine sweat glands, appear at all sites of the body. Involvement of the male genitalia is rare; however, syringomas should be considered as a clinical differential diagnosis to condylomata, lichen planus, and bowenoid papulosis. A proper diagnosis is possible only by histologic examination. Familial occurrence of multiple syringomas seems to be common, thus autosomal dominant inheritance is likely. An interesting hypothesis of etiology is the suggestion that some of the eruptive lesions may start as an inflammatory process. Treatment options of syringoma are generally unsatisfactory.Syringomas are most common on the eyelids, the nipples and the female genitalia. Different sites may be affected at the same time. Syringomas are typically skin-coloured to pink, but may appear yellow, translucent, or cystic. They are usually observed in symmetric, bilaterally distributed clusters.They may occur in successive crops at any age, an increased frequency is observed at puberty [1. The mean age of patients was 29 years, the mean delay from onset to demand for treatment was 6 years. An association with hormonal factors has been suggested, in particular the size of vulvar syringomas may increase during pregnancy. Involvement of the male genitalia is rare, only few cases have been reported [2-4]. A proper diagnosis of syringoma is possible only by histologic examination. Soler-Carrillo et al. described 27 syringomas among 67,000 histologic specimens (1:2,500) from skin biopsies. In only 11 cases, was the clinical diagnosis correct 芦syringoma禄. Histologically, syringomas are easily diagnosed by the accumulation of small ducts, some of which have comma-like tails, lined by two rows of epithelial cells. The histological differential diagnosis includes adnexal carcinoma, clear cell syringoma, and chondroid syringoma.