In Utero and Childhood Polybrominated Diphenyl Ether (PBDE) Exposures and Neurodevelopment in the CHAMACOS Study

摘要

Polybrominated diphenyl ether (PBDEs) flame retardant chemicals, used in the manufacture of furniture, infant products, and electronics, are ubiquitous in U.S. households (Sj?din et al. 2008). An unintended consequence of California's Technical Bulletin 117 (TB 117)-a fire safety law promulgated in the 1970s which requires that furniture, baby, and other household products resist open flame (California Department of Consumer Affairs 2000; Zota et al. 2008)—is that PBDE concentrations in California children are now among the highest measured worldwide (Eskenazi et al. 2011). Until 2005, the predominant chemical flame retardant used to comply with TB 117 was pentaBDE (comprising congeners BDEs 47, 99, 100, and 153).