Binding of fc receptors on blood T and B cells with IgG from healthy cows and cows with chronic lympholeukemia.

摘要

Pure population of T and B cells was obtained by a combined method consisting in lymphocyte fractionation through Nylon wool and precipitation of E-rosettes in 17% Verograffin density gradient. Scatchard analysis showed that T and B cells isolated from the blood of healthy cattle bind similar quantities of IgG molecules. Binding of IgG to Fc receptors of T and B cell isolated from animals with chronic lympholeukemia increases. The expression of Fc receptors for IgG is changed in cattle with chronic lympholeukemia.