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首页> 外文期刊>Bulletin of experimental biology and medicine >Effect of uridine of presynaptic NMDA and kainate receptor of rat brain cortex.
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Effect of uridine of presynaptic NMDA and kainate receptor of rat brain cortex.

机译:突触前NMDA的尿苷和大鼠大脑皮层的海藻酸酯受体的作用。

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摘要

It was demonstrated that uridine affects presynaptic NMDA and kainite receptors of rat brain cortex. Uridine considerably inhibited (45)Ca2+ uptake into synaptoneurosomes (IC50 = 7.1 x 10(-12) M) under conditions NMDA stimulation and increased it under conditions AMPA stimulation (157.8%).
机译:已证明尿苷影响大鼠脑皮质的突触前NMDA和kainite受体。尿苷在NMDA刺激条件下显着抑制(45)Ca2 +摄取到突触神经小体中(IC50 = 7.1 x 10(-12)M),在AMPA刺激条件下增加(157.8%)。

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