The therapeutic effect of combined cryotherapy, paramomycin, and intralesional meglumine antimoniate in treating lupoid leishmaniasis and chronic leishmaniasis.

摘要

Chronic or recurrent leishmaniasis (also called lupoid leishmaniasis) is one of the least common clinical presentations of cutaneous leishmaniasis. In contrast to the self-healing oriental sore, chronic leishmaniasis is characterized by persistent lesions and the parasite is thought to be maintained inside the macrophages. This chronic condition typically follows acute cutaneous leishmaniasis (CL), and in the majority of cases, Leishmania tropica is the causative agent. It has a broad range of clinical presentation, including brown to red papules or yellowish-brown papules that are characteristically present at the margin of the scarred area. These papules gradually coalesce to produce a plaque, which is very much similar to cutaneous lesions of lupus vulgaris (even the apple-jelly nodules are similar in both lesions). These lesions usually aggravate in the summer and may even produce crusts or concentric rings.