HYDROPHILIC PLATINUM COMPLEXES OF N-2-HYDROXYETHYL- AND N,N-DI(2-HYDROXYETHYL)-N'-BENZOYLTHIOUREA LIGANDS - CRYSTAL AND MOLECULAR STRUCTURE OF N,N-DI(2-HYDROXYETHYL)N'-BENZOYLTHIOUREA

摘要

The crystal and molecular structure of hydrophilic N,N-di(2-hydroxyethyl)-N'-benzoylthiourea (H(3)L(4)) has been determined. This ligand coordinates to Pt(II), Pd(II) and Ni(II) in a bidentate manner yielding essentially neutral complexes of the type cis-[Pt(H(2)L(4))(2)]. By contrast, N-(2-hydroxyethyl)-N'-benzoylthiourea (H(3)L(5)) behaves like a monodentate thiourea ligand and reacts with Pt(II) to yield a mixture of cis and trans complexes of [Pt(H(3)L(5))(2)Cl-2]. The (+)FAB mass spectrum of the latter complexes is also discussed. [References: 19]