Delays in the treatment of STEMI: remarkable progress, room for improvement

摘要

The concept 'time is myocardium' arose from animal models in the late 1970s [l] and was confirmed by clinical trials using both fib-rinolytic therapy and primary percutaneous coronary intervention (PCI) [2,3]. Treatment delays appear to be less critical for PCI compared with fibrinolytic therapy. For example, results from the Swedish RIKS-HIA registry indicate the benefit of fibrinolytic therapy declines after a 2-h delay, but not with PCI and, at every time point, PCI remains superior to fibrinolysis [4].