Trabecuiecfomy Success Rate among Glaucoma Patients in Kelantan, Malaysia

摘要

Objective: To determine the five year trabeculectomy success rate among glaucoma patients treated at Hospital Universiti Sains Malaysia (HUSM).Design: A retrospective record review.Materials and Methods: This study was conducted among 96 glaucoma patients (96 eyes) who underwent trabeculectomy from 1~(st) January 1990 to 31~(st) July 2006 in HUSM, Kelantan, Malaysia. Additional follow up of one year after the recruitment of the study subjects was done from 1st August 2006 to 31s' July 2007. All patients who fulfilled the selections criteria were included in the study. The medical records were reviewed by a single researcher with the help of senior consultant of ophthalmology and important information on the variables of interest and trabeculectomy outcome states were collected and recorded into a clinic form. The Kaplan Meier analysis was used in statistical analysis.Results: The median trabeculectomy success time was 18.8 months and the overall trabeculectomy success rate was 36.1% (95% CI 25.6, 46.8) at five year. The patients without ocular surgery [42.2% (95% CI 30.3, 53.5)] demonstrated higher trabeculectomy success rate compared to those with previous ocular surgery [0% (95% CI 0, 0)] prior to trabeculectomy at five year post trabeculectomy and the difference was statistically significant (p = 0.008).Conclusion: Trabeculectomy success rate for glaucoma patients at HUSM was acceptably low. The use of antimetabolites during trabeculectomy is highly recommended in our population especially those with previous ocular surgery.