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Diffuse Idiopathic Skeletal Hyperostosis Cases Found in Joseon Dynasty Human Sample Collection of Korea

机译:韩国朝鲜王朝人类样本采集中发现的弥漫性特发性骨骼肥大症病例

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Diffuse idiopathic skeletal hyperostosis (DISH) is a disorder showing hyperostosis of the spinal column and ossification of extraspinal ligaments or tendons. The prevalence of DISH has been found to be higher in historic peoples of the upper- and ruling classes, and in fact was closely correlative with nutritional and high-caloric diets. DISH is also known to be a function of genetic factors; as such, there have been very few cases of DISH found among the specimens of Asian skeletal collections. In our osteoarchaeological study on the Joseon Dynasty Human Sample Collection (JDHSC), we found four DISH instances among the 96 cases (4.17%) we examined. This prevalence is not so different from those discovered in already-published studies on collections in Europe and other regions. However, as already stated, it must be considered that most of the JDHSC individuals we examined were remains of people from the highest social classes of 16th–18th century Joseon society. Therefore, when collections from medieval European monastic sites, the appropriate control from well-fed populations, were used for comparison, the prevalence of DISH was found to be far lower among the JDHSC. Reports on DISH from examinations of collections in Asian countries have been spotty, leaving gaps in the social-strata spectrum. Further researches into the prevalence of DISH among the different social strata of ancient or medieval Asian peoples are still required.
机译:弥漫性特发性骨骼肥大症(DISH)是一种表现为脊柱肥大和脊柱外韧带或肌腱骨化的疾病。在上层和统治阶级的历史悠久的人民中,发现DISH的患病率更高,实际上与营养和高热量饮食密切相关。众所周知,DISH是遗传因素的作用。因此,在亚洲骨骼收藏标本中几乎没有发现DISH病例。在我们对朝鲜王朝人类样本收集(JDHSC)的骨考古学研究中,我们检查了96例病例(4.17%)中发现了四个DISH实例。这种流行与欧洲和其他地区已经发表的关于收藏的研究没有太大不同。但是,正如已经指出的那样,必须考虑到,我们检查的大多数JDHSC个人都是16至18世纪朝鲜社会最高社会阶层的人的遗骸。因此,当使用欧洲中世纪修道院遗址的收集物,来自饮食充足的种群的适当对照进行比较时,发现JDHSC中DISH的患病率要低得多。来自亚洲国家的藏品检查中有关DISH的报告参差不齐,在社会阶层谱图中留下了空白。仍然需要对古代或中世纪亚洲人民不同社会阶层中DISH患病率的进一步研究。

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